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Epileptic Disorders

Epileptic Disorders is the leading forum where all experts and medical studentswho wish to improve their understanding of epilepsy and related disorders can share practical experiences surrounding diagnosis and care, natural history, and management of seizures.
Epileptic Disorders is the official E-journal of the International League Against Epilepsy for educational communication. As the journal celebrates its 20th anniversary, it will now be available only as an online version. Its mission is to create educational links between epileptologists and other health professionals in clinical practice and scientists or physicians in research-based institutions. This change is accompanied by an increase in the number of issues per year, from 4 to 6, to ensure regular diffusion of recently published material (high quality Review and Seminar in Epileptology papers; Original Research articles or Case reports of educational value; MultiMedia Teaching Material), to serve the global medical community that cares for those affected by epilepsy.

 

Ahead of print

Original article

Efficacy and tolerability of the modified Atkins diet in children with drug-resistant genetic generalized epilepsy
Shawn Kacker, Douglas R. Nordli Jr, Chalongchai Phitsanuwong
Online since 27/11/2021

Independent risk factors for seizures in critically ill patients on continuous EEG
Pedro V.F. Naves, Luis O. Caboclo
Online since 27/11/2021

Beyond neonatal seizures - epileptic evolution in preterm newborns: a systematic review and meta-analysis
Raffaele Falsaperla, Laura Mauceri, Milena Motta, Giovanni Prezioso, Martino Ruggieri, Francesco Pisani
Online since 26/11/2021

Evaluation of real-world effectiveness of perampanel in Japanese adults and older adults with epilepsy
Yushi Inoue, Kenta Sumitomo, Kazuhiro Matsutani, Mika Ishii
Online since 17/11/2021

Determinants of postictal agitation and recovery after tonic-clonic seizures in generalized and focal epilepsy
Aman Dabir, Salman Zahoor, Bassel W. Abou-Khalil
Online since 17/11/2021

Burden of seizures and comorbidities in patients with epilepsy: a survey based on the tertiary hospital-based Epilepsy Syndrome Registry in Japan
Yushi Inoue, Shin-ichiro Hamano, Masaharu Hayashi, Hiroshi Sakuma, Shinichi Hirose, Atsushi Ishii, Ryoko Honda, Akio Ikeda, Katsumi Imai, Kazutaka Jin, Akiko Kada, Akiyoshi Kakita, Mitsuhiro Kato, Kensuke Kawai, Tamihiro Kawakami, Katsuhiro Kobayashi, Toyojiro Matsuishi, Takeshi Matsuo, Shin Nabatame, Nobuhiko Okamoto, Susumu Ito, Akihisa Okumura, Akiko Saito, Hideaki Shiraishi, Hiroshi Shirozu, Takashi Saito, Hidenori Sugano, Yukitoshi Takahashi, Hitoshi Yamamoto, Tetsuhiro Fukuyama, Ichiro Kuki, (Japan Rare Epilepsy Syndrome Registry Group: JRESG)
Online since 17/11/2021

Children with seizures and radiological diagnosis of focal cortical dysplasia: can drug-resistant epilepsy be predicted earlier?
Ido Ben Zvi, Noelle Enright, Felice D’arco, M Zubair Tahir, Aswin Chari, J Helen Cross, Christin Eltze, Martin M Tisdall
Online since 10/11/2021

Limb loss experience evoked by electric cortical stimulation
Guiliang Hao, Xueyuan Wang, Hao Yan, Liu He, Duanyu Ni, Liang Qiao, Xiaohua Zhang, Kaijia Yu, Tao Yu
Online since 10/11/2021

Etiology and prognostic significance of ictal EEG patterns in patients with non-convulsive seizures
Jaysingh Singh, Mangala Gopal, Assad Amin, Juan Peng
Online since 10/11/2021

Relationship between location of epileptic focus and occurrence during sleep versus wakefulness
Pooja Narang, Divyani Garg, Garima Shukla, Mamta Bhushan Singh, Achal Srivastava, Anupama Gupta, Ashish Suri, Ajay Garg, CS Bal, Deepti Vibha, Awadh Kishor Pandit, Kameshwar Prasad
Online since 10/11/2021

Prevalence of various risk factors associated with new-onset epilepsy after the age of 50: a retrospective population-based study
Emilija Cvetkovska, Marija Babunovska, Bojan Boskovski, Igor Kuzmanovski, Nikolina Tanovska, Gordana Kiteva Trencevska
Online since 10/11/2021

Epilepsy features in ARID1B-related Coffin-Siris syndrome
Jacopo Proietti, Elisabetta Amadori, Pasquale Striano, Emilia Ricci, Duccio Maria Cordelli, Cristina Bana, Robertino Dilena, Elena Gardella, Jens Erik Klint Nielsen, Francesco Pisani, Tommaso Lo Barco, Elena Fiorini, Elena Fontana, Francesca Darra, Bernardo Dalla Bernardina, Gaetano Cantalupo
Online since 04/11/2021

Effectiveness and safety of perampanel in Chinese paediatric patients (2–14 years) with refractory epilepsy: a retrospective, observational study
Rui Qu, Yuanyuan Dai, Xuqin Chen, Rui Li, Min Liu, Yali Zhu
Online since 04/11/2021

Seizures in autoimmune encephalitis: specific features based on a systematic comparative study
Louis Cousyn, Virginie Lambrecq, Marion Houot, Natalia Shor, Vi-Huong Nguyen-Michel, Valerio Frazzini, Sophie Dupont, Sophie Demeret, Vincent Navarro
Online since 28/10/2021

Elective inpatient video-EEG monitoring during the COVID-19 pandemic
Nikoli D. Brown, Mohammad Dastjerdi, Paul Herrmann, Joshua Loeb, Richard Tang-Wai, Jennifer Veltman, Travis E. Losey
Online since 28/10/2021

OCLN gene variants identified in three patients with severe neurodevelopmental disorder associated with epilepsy, intellectual disability and malformation of cortical development
Tulay Oncu Oner, Aycan Unalp, Semra Hiz, Erhan Bayram, Ismail Kaytan, Sultan Cingoz
Online since 28/10/2021

Vortioxetine suppresses epileptiform activity and cognition deficits in a chronic PTZ-induced kindling rat model
Mehmet Taskiran, Gokhan Unal
Online since 28/10/2021

Pentobarbital coma therapy for super-refractory status epilepticus and in-hospital mortality: an observational study
Seungyon Koh, Tae-Joon Kim, Tae-Sung Lim, Jin Soo Lee, Byung Gon Kim, Sun Ah Park, Kyoon Huh, Jun Young Choi
Online since 14/10/2021

MiRNA-29a serves as a promising diagnostic biomarker in children with temporal lobe epilepsy and regulates seizure-induced cell death and inflammation in hippocampal neurons
Yifei Wu, Yanrui Zhang, Shuxia Zhu, Chunmei Tian, Yanyan Zhang
Online since 06/10/2021

Seminar in epileptology

Acute symptomatic seizures: an educational, evidence-based review
Matthias Mauritz, Lawrence J Hirsch, Peter Camfield, Richard Chin, Raffaele Nardone, Simona Lattanzi, Eugen Trinka
Online since 19/11/2021

Epilepsy in adults with neurodevelopmental disability - what every neurologist should know
Lance V. Watkins, Christine Linehan, Christian Brandt, Francesca Snoeijen-Schouwenaars, Paula McGowan, Rohit Shankar
Online since 10/11/2021

Case vignette

Adult new-onset status epilepticus secondary to en coup de sabre: a case report and review of the literature
Hera A. Kamdar, Jan Bittar, Sarita Maturu
Online since 27/11/2021

Continuous spikes and waves during slow sleep related to sulthiame?
Roberto Horacio Caraballo, Santiago Galicchio
Online since 10/11/2021

Subtotal hemispherotomy for late-onset spasms after anti-myelin oligodendrocyte glycoprotein antibody-positive acute haemorrhagic leukoencephalitis
Naohiro Yamamoto, Ichiro Kuki, Shizuka Nagase, Takeshi Inoue, Megumi Nukui, Shin Okazaki, Noritsugu Kunihiro, Takehiro Uda, Masataka Fukuoka, Jun Kubota, Shin-Ichiro Hamano, Hiroshi Sakuma, Hisashi Kawawaki
Online since 21/10/2021

Super-refractory status epilepticus related to COVID-19 in a paediatric patientwith PRRT2 mutation
Diane Vergara, Carla Rubilar, Scarlet Witting, Mónica Troncoso, Roberto Caraballo
Online since 21/10/2021

Early diagnosis and experimental treatment with fenfluramine via the Investigational New Drug mechanism in a boy with Dravet syndrome and recurrent status epilepticus
Sara Trowbridge, Annapurna Poduri, Heather Olson
Online since 21/10/2021

The epilepsy-movement disorder phenotypic spectrum and phenytoin-induced dyskinesia associated with GABRB3 pathogenic variants
Amaar Marefi, Myriam Srour
Online since 21/10/2021

Auditory and emotion-sensitive jerks in a patient with subacute sclerosing panencephalitis
Ruchika Tandon, Varsha Ambwani
Online since 21/10/2021

Encephalocele-associated temporal lobe epilepsy and skull fibrous dysplasia: a report of two cases
Kelsey M. Smith, Benjamin C. Cox, Ojore O. Jones, Amy L. Kotsenas, Jamie J. Van Gompel, David B. Burkholder, Lily C. Wong-Kisiel
Online since 21/10/2021

Repetitive focal seizures evolving into ictal asystole: a case report with 18 seizures during video-EEG monitoring
Anna Stefánsdóttir, Anne Sabers, Annette Sidaros, György Rásonyi, Noémi Becser Andersen, Marius Kløvgaard
Online since 14/10/2021

Deep brain stimulation (DBS) of anterior nucleus thalami (ANT) in female epilepsy patients during pregnancy and delivery: experience from two cases
Patrick M. House, Anja Herzer, Irene Lorenzi, Philipp Niedernhöfer, Berthold Voges, Stefan Stodieck, Manfred Westphal, Miriam Schaper, Johannes A. Koeppen, Wolfgang Hamel
Online since 07/10/2021

List of reviewers for manuscripts published in 2021

List of reviewers for manuscripts published in 2021

Online since 28/10/2021

ILAE Psychology Task Force Report <td:inline-figure xmlns:td="http://www.thomsondigital.com/xml/common/dtd"><td:link locator="fx

Cochrane systematic review and meta-analysis of the impact of psychological treatment on health-related quality of life in people with epilepsy: an update by the ILAE Psychology Task Force, highlighting methodological changes
Rosa Michaelis, Venus Tang, Sarah J. Nevitt, Janelle L. Wagner, Avani C. Modi, W. Curt LaFrance Jr, Laura H. Goldstein, Milena Gandy, Rebecca Bresnahan, Kette Valente, Kirsten A. Donald, Markus Reuber
Online since 04/11/2021

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Imaging characteristics of temporopolar blurring in the context of hippocampal sclerosis
Carlos Andrés Clavijo Prado, Paolo Federico, Andrea Bernasconi, Boris Bernhardt, Lorenzo Caciagli, Luis Concha, Yotin Chinvarun, Graeme Jackson, Victoria Morgan, Stefan Rampp, Anna Elisabetta Vaudano, Irene Wang, Shuang Wang, Bruna Cunha Zaidan, Fabio Rogerio, Fernando Cendes
Online since 20/11/2021

Clinical commentary

Video game-induced reflex seizures via a smartphone
Antonella Riva, Erika Rebessi, Eliana Parente, Maurizio Viri, Pasquale Striano, Antonino Romeo
Online since 23/11/2021

Focal status epilepticus may trigger relapse of primary angiitis of the CNS
Antoine Guilmot, Sofia Maldonado Slootjes, Thierry Duprez, Julie Lelotte, Martin Lammens, André Peeters, Susana Ferrao Santos
Online since 23/11/2021

De novo psychosis after left temporal lobectomy: a case of forced normalization?
Marie Arthuis, Stanislas Lagarde, Aileen Mcgonigal, Fabrice Bartolomei
Online since 20/11/2021

Progression of alternating hemiplegia of childhood-related focal epilepsy to electrical status epilepticus in sleep with reversible encephalopathy
Derek Neupert, Puya Abbassi, Lyndsey Prange, Robert Flamini, Mohamad A. Mikati
Online since 19/11/2021

ACTH for epileptic spasms in Leigh syndrome with SLC19A3 mutation can induce status dystonicus
Hiroki Hoshino, Hideaki Kanemura
Online since 19/11/2021

Epilepsia partialis continua associated with the p.Arg403Cys variant of the DNM1L gene: an unusual clinical progression with two episodes of super-refractory status epilepticus with a 13-year remission interval
Sara Minghetti, Roberto Giorda, Massimo Mastrangelo, Laura Tassi, Nicoletta Zanotta, Sara Galbiati, Maria Teresa Bassi, Claudio Zucca
Online since 18/11/2021

Major intra-familial variability in Unverricht-Lundborg disease
Amina Nasri, Sabrina Zidi, Imen Kacem, Saloua Mrabet, Mouna Ben Djebara, Amina Gargouri, Eric Leguern, Riadh Gouider
Online since 18/11/2021

Flashing lights and epileptic spasms: should we be routinely performing intermittent photic stimulation in infants?
Marvin H. Braun, Naureen Jooma, Morris H. Scantlebury
Online since 11/11/2021

De novo status epilepticus possibly related to battery depletion of anterior thalamic brain stimulator
Gadi Miron, Ido Strauss, Firas Fahoum
Online since 11/11/2021

Atypical presentation of sunflower epilepsy featuring an EEG pattern of continuous spike waves during slow-wave sleep
Esmeralda Nava, Andrea Capone Mori, Pasquale Striano, Georgia Ramantani
Online since 28/10/2021

Sexual orgasm as a trigger for reflex epilepsy
Ana Azevedo, Rita Rodrigues, Bárbara Teixeira, Peter Grebe
Online since 28/10/2021

Eyelid myoclonia with absences related to epileptic negative myoclonus
Atsuro Daida, Mina Yokoyama, Kaoru Yamamoto, Daisuke Hasegawa, Isao Kusakawa, Chuan-Yu Wang, Masaaki Ogihara
Online since 21/10/2021

Intracortical focal non-convulsive status epilepticus causing cerebral hypoxia and intracranial hypertension
José L. Fernández-Torre, Miguel A. Hernández-Hernández, David Mato-Mañas, Enrique Marco de Lucas, Elsa Gómez-Ruiz, Rubén Martín-Láez
Online since 21/10/2021

Room tilt illusion in epilepsy
Deema Fattal, Anne-Sophie Wattiez, Erik St Louis, Karina Gonzalez-Otarula, Rup Sainju
Online since 21/10/2021

Exacerbation of eyelid myoclonia in patients with epilepsy and eyelid myoclonia receiving cannabidiol
Ifrah Zawar, Linfa Franic, Prakash Kotagal, Elia Pestana Knight
Online since 14/10/2021

Review article

Knowledge gaps for functional outcomes after multilobar resective and disconnective pediatric epilepsy surgery: Conference Proceedings of the Patient-Centered Stakeholder Meeting 2019
Monika Jones, William B. Harris, M. Scott Perry, Marlene Behrmann, Joanna Christodoulou, Aria Fallah, Bryan Kolb, Frank Musiek, Lynn K. Paul, Klajdi Puka, Cynthia Salorio, Raman Sankar, Mary Lou Smith, Ahsan Moosa Naduvil Valappil, Patricia Walshaw, Howard L. Weiner, Raymond Woo, Phillip Zeitler, Taylor J. Abel
Online since 23/11/2021

Understanding the landscape of electrophysiology services for children in sub-Saharan Africa
Veena Kander, Joanne Hardman, Jo M Wilmshurst
Online since 28/10/2021

Electroclinical reasoning report

Ictal head roll: a seizure semiology from the anterior prefrontal lobe
Gabriela Tantillo, Hernan Nicolas Lemus, Nathalie Jetté, Saadi Ghatan, Fedor Panov, Dina Bolden, Madeline C. Fields
Online since 11/11/2021

Multimedia teaching material

Let's all repeat – palilalia may be epileptic!
Fábio A. Nascimento, Jay R. Gavvala
Online since 26/11/2021

Asymmetric eye movement artifacts on EEG, secondary to unilateral retinal detachment in patients with focal epilepsy
Karlo Toljan, Elia Pestana-Knight, Ahsan NV Moosa
Online since 14/10/2021