John Libbey Eurotext



Illuminating the nanoscopic world of viruses by fluorescence super-resolution microscopy Volume 25, issue 3, Mai-Juin 2021


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1 IRIM, Université de Montpellier, UMR 9004 CNRS,
1919, route de Mende,
34293 Montpellier
2 Cemipai, Université de Montpellier, UAR 3725 CNRS,
1919, route de Mende,
34293 Montpellier
* Correspondance

The recent revolution in optical fluorescence microscopy, supported by the optimization of both spatial resolution and acquisition speed, led to the ability to visualize nano-scaled objects. Currently, the use of a new generation of super-resolution fluorescence microscopes coupled to improved fluorescent probes gives the possibility to study the replicative cycle of viruses in living cells, at the single-virus and molecule level. In this review, after a brief chronological description of these new approaches, we highlight several examples of super-resolution microscopies that have allowed to revisit our understanding of several human viruses and of host-pathogen interactions.