The impact of sexual dysfunction in people with schizophrenic disorder treated with antipsychotics: a review of the literature Ahead of print


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1 Hôpital Paul-Guiraud, 94800 Villejuif, France
2 GHU Paris Psychiatrie & Neurosciences, Paris, France
* Correspondance : Louise Michaudel <louise.michaudel@hotmail.fr>
© Aius. Publié par John Libbey Eurotext. Tous droits réservés


Schizophrenia is one of the most severe psychiatric diseases. Antipsychotic medications are the standard, first-in-line treatment, but have many adverse effects including sexual dysfunctions. How sexual dysfunctions may impact people with schizophrenia on AP medications?


PRISMA methods were used in the review of the literature. Investigated databases include PsycInfo, Pubmed and Embase.


Literature consensus suggests that sexual dysfunctions are common side effect experienced by patient with schizophrenia on AP medications. The origin is multifactorial. The psychometric tools typically used to evaluate sexual dysfunctions support clinical judgement through symptom characterization. These symptoms have been shown to impact patient self-esteem, interpersonal relations and overall quality of life. However, sexual dysfunctions often remain undiscussed by the patients and the professionals.


Sexuality is a complex subject influenced by many factors including biological, psychological, social, cultural and interpersonal. Programs about sexuality could help patient to the recovery and therefore improved quality of life. To this end, targeted sexual healthcare training may benefit the psychiatric community.


Improved therapeutic alliance in assessing sexual dysfunction is important. Advanced practitioners nurse can provide the development and standardization of sexual healthcare practices to help improve the quality of life of patients with schizophrenia.