Journal de Pharmacie Clinique


Therapeutic optimization in patients in acute geriatric care at University Hospital of Montpellier: follow-up one month after discharge from hospital Volume 41, issue 4, Décembre 2022


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1 Unité de médecine interne et de soins aigus gériatriques, CHU de Montpellier, 34090 Montpellier, France
2 Pharmacie à usage intérieur, Centre hospitalier de Clermont-l’Hérault, 34800 Clermont-l’Hérault, France
Correspondance : C. Estournet

Pharmacological changes related to aging or polymedication expose elderly to drug-related iatrogenia. The fight against potentially inappropriate medications prescription in these patients is therefore necessary. We assessed the impact of the collaboration between physicians and pharmacists within the acute geriatric care unit of the University Hospital of Montpellier on the treatment of elderly patients. Moreover, we assessed the follow-up of hospital therapeutic changes by general practitioners one month after the discharge of the patients from hospital.


After inclusion of the patients between January 2nd and March 16th, 2020, we called their dispensary pharmacist and general practitioner from February 1st to April 30th, 2020 to obtain their treatment one month after their discharge from the hospital and the opinion of these healthcare professionals on ways to improve the management of medication for elderly patients.


The collaboration between physicians and pharmacists in the hospital has significantly reduced the number of potentially inappropriate drugs per prescription: their prevalence has decreased from 57.6 % to 23.7 % between admission and discharge from the 59 study patients. Although increased one month after the release of the patients (27.1 %), the prevalence has remained significantly lower than what we found before the hospital therapeutic optimization suggesting the general practitioners’ agreement with therapeutic changes done in the hospital.


The improvement of collaboration between hospitals and local healthcare services in the one hand and between dispensary pharmacists and general practitioners in the other hand are many perspectives to optimize drug management of elderly.