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Le cryptochrome : un acteur clé du mécanisme d’action biologique des champs magnétiques ? Volume 18, issue 2, March-April 2019

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This news is based on the following articles:

Sherrard RM, Morellini N, Jourdan N, et al. Low-intensity electromagnetic fields induce human cryptochrome to modulate intracellular reactive oxygen species. PLoS Biol 2018 ; 16 : e2006229. doi : 10.1371/journal.pbio.2006229

Landler L, Keays DA. Cryptochrome: the magnetosensor with a sinister side? PLoS Biol 2018 ; 16 : e3000018. doi : 10.1371/journal.pbio.3000018

 

Finding that production of reactive oxygen species via cryptochromes represents a general biological response to exposure to low-intensity magnetic fields, the authors of the first article believe that this mechanism may explain that exposure may have beneficial or harmful effects, depending on whether it generates moderate or excessive oxidative stress. Since “extraordinary statements require extraordinary evidence,” the authors of the commentary article published at the same time call for caution in interpreting these experimental results, to avoid any hasty extrapolation.

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