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Virologie

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Une question de terrain : signification de la persistance de l’ADN du parvovirus B19 Volume 19, issue 4, Juillet-Août 2015

Authors
1 Groupe hospitalier Saint-Louis Lariboisière Fernand-Widal,
Pôle biologie-pathologie-physiologie,
Université Paris-Diderot Paris-7,
1, avenue Claude-Vellefaux
Paris 75010, France
2 Laboratoire des agents infectieux et hygiène, CHU Saint-Étienne,
Saint-Étienne, France
3 Laboratoire de Virologie,
CHU Necker Enfants Malades,
Paris, France
4 Hôpital des Enfants-Hôpital Pellegrin,
Unité d’hémato-oncologie pédiatrique,
Cerevance, Bordeaux, France
* Tirés à part

The discovery of the human parvovirus B19 was done by Yvonne Cossart in 1975. In addition to fifth disease and aplastic crisis numerous clinical manifestations have been associated with B19 infections. Routine virological diagnosis is made by the detection of specific IgM and sometimes by the detection of viral DNA. Some clinicians are perplexed by the persistence of B19 DNAemia after acute infections. In this point of view we try to discuss this problematic.