Laboratoire de neuroimmunovirologie, Centre Armand-Frappier Santé Biotechnologie, Institut national de la recherche scientifique (INRS), Université du Québec, Laval, Québec, Canada H7V 1B7
Laboratoire de microbiologie, CHU de Sainte-Justine, Montréal, Québec, H3T 1C5, Canada
Faculté de médecine, département de microbiologie, infectiologie et immunologie. Université de Montréal, Montréal, Québec, H3C 3J7, Canada
Correspondance : P.J. Talbot : M. Desforges
For a large proportion of mankind, the word coronavirus only became a reality in the year 2020, as it was the cause of one of the worst pandemics of the last two centuries. Nevertheless, well before this ominous moment, human coronaviruses (HCoV) were well characterized respiratory pathogens since the 1960s. The most recent discovery of SARS-CoV and MERS-CoV showed that coronaviruses have a pandemic potential with important consequences. With the COVID-19 pandemic caused by SARS-CoV-2, this potential is now certain. Moreover, accumulating evidence support an association between coronaviruses and extra-respiratory pathologies, in particular of the central and peripheral nervous system. Linked or not with a neuro-invasive and neurotropic potential, it is now clear that coronaviruses can be associated with the development of neurological disorders.