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Rotavirus vaccination, where do we stand? Volume 25, issue 3-4, July-December 2023

Author
1 Centre Hospitalier Princesse Grace, Service de Pédiatrie Néonatalogie, 1 avenue Pasteur, 98000 Monaco
2 Groupe de Pathologie Infectieuse Pédiatrique
3 Infovac France
* Correspondance : H. Haas

Rotavirus infections are the main cause of viral acute gastroenteritis which particularly affects infants and children under 5 years of age. Without vaccination, given the extreme contagiousness of the virus, almost all children will experience at least one episode of acute rotavirus gastroenteritis before the age of 5. In the absence of specific treatment, vaccination represents the best weapon for preventing complications. Rotavirus vaccination is recommended in more than 100 countries worldwide. The effectiveness in real life has been widely demonstrated, notably with a significant reduction in morbidity and the burden of disease on hospitalizations and emergency consultations. The very low excess risk of intussusception in the 7 days following the first dose does not call into question the benefit/risk balance, and no country has interrupted its vaccination program for reasons of tolerance.

This oral vaccination is now recommended and reimbursed in France for all infants, including premature babies.