JLE

Médecine de la Reproduction

MENU

Anti-Mullerian hormone and male puberty Volume 16, issue 1, Janvier-Février-Mars 2014

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Author
Hôpital Bicêtre et faculté de médecine Paris 11, 78, avenue du Général Leclerc, 94270 Le Kremlin Bicêtre, France ; Centre de référence des anomalies rares du développement sexuel, 78, avenue du Général Leclerc, 94270 Le Kremlin Bicêtre, France
* Tirés à part

AMH is a glycoprotein secreted essentially by fetal and prepubertal Sertoli cells in boys. FSH stimulates testicular AMH production in these periods of life. During puberty, AMH production is inhibited by the increase of intratesticular testosterone concentration and the onset of germ cell meiosis. The inhibitory effect of androgens on AMH overrides the positive effects of FSH. The secretion of AMH in situations of precocious puberty, delayed puberty, hypogonadotropic hypogonadism and testicular insufficiency is described in this article.