Magnesium Research


Impact of magnesium supplementation, in combination with vitamin B6, on stress and magnesium status: secondary data from a randomized controlled trial Volume 33, issue 3, July-August-September 2020


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1 Global Medical Nutritionals, Consumer Healthcare, Sanofi, Paris, France
2 Clinical Pharmacology Center, INSERM CIC 1405, University Hospital Clermont-Ferrand, France
3 Université Clermont Auvergne, INRAE, UNH, Unité de Nutrition Humaine, Clermont-Ferrand, France
4 Statistics, Consumer Healthcare, Sanofi, Paris, France
* Correspondence


Primary findings from a recent study reported that magnesium supplementation significantly reduced stress in severely stressed subjects with low magnesemia, and additional vitamin B6 enhanced this effect. The mechanism by which combining magnesium and vitamin B6 leads to reduced stress in these subjects remains to be elucidated. This secondary analysis investigated the impact of magnesium and vitamin B6 supplementation and perceived stress on erythrocyte magnesium levels, as a marker of body magnesium status.

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