John Libbey Eurotext



Nefopam in general medicine: what interest and under what conditions? Volume 18, issue 9, November 2022


  • Figure 1.
1 Médecin généraliste, 1 rue Saint Jean Baptiste, 66650 Banyuls-sur-mer
2 Psychiatre, 53 avenue Giraudoux, 66000 Perpignan
3 Interne en médecine générale, 34000 Montpellier
4 Externe, 49000 Angers
Correspondance : P. Frances

Nefopam (Acupan®) is a centrally acting non-opioid analgesic used for the treatment of moderate to severe pain. Similar to a level 1 analgesic in view of the WHO pain classification, it is a 1st or 2nd line drug depending on the intensity of the pain, but due to a significant risk of drug dependence, it should not be used in the context of chronic pain. What can be its interest in general medicine, and under what conditions?