John Libbey Eurotext

Hépato-Gastro & Oncologie Digestive


Traitement des métastases hépatiques des cancers de l'estomac Volume 17, issue 2, mars-avril 2010

Département de Chirurgie Digestive et Viscérale, CHU de Caen, Service de Gastroentérologie, Centre François Baclesse et CHU de Caen

Liver metastasis from gastric cancers may be synchronous or occur later, after the gastrectomy. They are often diffuse and associated with advanced disease, conducting the patient to a palliative treatment. However, these metastases can be isolated and resectable, which must lead to discuss a surgical treatment. Indeed, analysis of the literature shows that surgical resection of liver metastases may be in curative intent in selected cases, since the survival after resection is about 30% at 5 years. The prognostic factors are related to stage of gastric tumor, the uniqueness of the metastasis, its size and the achievement of full resection. If chemotherapy is the reference in the metastatic gastric cancer, in resectable metastasis cases, chemotherapy combined with surgery should be discussed on a case by case because there is so far no data available on its usefulness and its nature, given the lack of therapeutic trials in this rare situation.