Hépato-Gastro & Oncologie Digestive


Irritable bowel syndrome – Evolutionary aspects: Natural history, clinical presentation, quality of life Volume 21, supplement 2, Septembre 2014


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CHU de Nantes,
Institut des Maladies de l’Appareil Digestif,
CIC-04 et INSERM U913,
CHU Hôtel Dieu,
Place A Ricordeau,
44093 Nantes Cedex,
* Tirés à part

Heterogenous and variable characteristics of symptoms in patients with irritable bowel syndrome (IBS) do not allow to demonstrate clear prognostic course in these patients. However it has been observed that in a number of patients, symptoms are occurrring as short attacks for a couple of days alternating with periods with no or low intensity symptoms. When considering long term period symptoms remain present in the majority of IBS patients; it has been reported that after 7 years two thirds of them still have functional gastrointestinal symptoms. In fact clinical expression of symptoms often varies in these patients with alternating functional dyspepsia and SII symptoms. Usually when considering long period, intensity of symptoms is rather decreasing. Bringing informations as well as supportive explanations on the disease with person-centered care is of help although this is a long-term learning process. It may introduce a better and positive physician-patient interaction which usually allows a better improvement of symptoms. Quality of life is altered in IBS patients and correlates with severity of symptoms and perceived impairment. Finally in IBS patients, four aspects of life are to specifically consider: basic functioning (walking, working and sleeping), relationships, self-image and psychological well-being.