Registre Bourguignon des Cancers Digestifs ; INSERM EPICAD LNC-UMR1231 ; UFR Santé Bourgogne Franche Comté, Dijon ; CHU Dijon, F-21079
The incidence of colorectal cancer increased in France until the 2000s’ then regularly decreased in men with a -1.4% mean annual variation over the last ten years, whereas incidence remained stable in women. Time trends in incidence for this cancer varied according to its sub location along the gut. The decrease in incidence was higher for rectal than for colon cancers. Even if rare, incidence in young patients less than 40 years increased in recent cohorts.
The proportion of colorectal cancer in the overall French cancer prevalence was 13%. In 2018, 152,000 patients had a colorectal cancer diagnosed in the 5 previous years.
The prognosis of colorectal cancer improved over time. Net 5-year survival increased in males from 52% for cancers diagnosed between 1989 and 1993 to 60% for those diagnosed between 2005 and 2010. This trend concerned all age classes but was less marked in patients aged 75 and over.
The national colorectal screening and the introduction of recent immunological tests should decrease the mortality for this cancer and, at term, should decrease its incidence too subject to a sufficient participation.