Hépato-Gastro & Oncologie Digestive


Liver adenoma: What is new? Volume 20, issue 4, Avril 2013


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Hôpital Beaujon, pôle des maladies de l’appareil digestif, service de chirurgie hépato-bilio-pancréatique, 100 boulevard du Général Leclerc, 92110 Clichy, France ; Université Paris 7

Liver adenomas are rare benign liver tumours, defined by the monoclonal proliferation of hepatocytes. On imaging, they belong with hepatocellular carcinoma and focal nodular hyperplasia (FNH) to the group of tumors that show early enhancement at the arterial phase. Adenomas are usually single tumours but can be multiple and form an heterogeneous group at the molecular level. They are not exclusively observed in women taking oral contraceptives. They have an inherent risk of bleeding and malignant transformation that differentiates them from FNH for which these risks are nil. The risk of bleeding increases with tumour size and that of malignant transformation with size, gender and phenotype of the adenoma. These findings have changed their management.