Faculté de médecine, Université de Reims Champagne-Ardenne, EA 3797, Reims, France, Département de gérontologie clinique, Hôpital Maison Blanche, CHU de Reims, France, Unité d’aide méthodologique, Hôpital Maison Blanche, CHU de Reims, France
- Key words:
bibliographic search, quality of life, instruments, Alzheimer's disease, dementia, ADCS-ADL, AD co-operative study-activities of daily living inventory, ADL, Activities of daily living, CAMCOG, Cognitive and self-contained part of the Cambridge examination for mental disorders of the elderly (Camdex), CANE, Camberwell assessment of need forthe elderly, CAPE-BRS, Clifton assessment procedures for the elderly-behaviour rating scale, CBS, Challenging behaviour scale, CDR, Clinical dementia rating, CERAD/BRSD, Consortium to establish a registry for Alzheimer's disease-behaviour rating scale for dementia, CSDD, Cornell scale for depression in dementia, DAD, Disability assessment for dementia, GDS, Geriatric depression scale, IADL, Instrumental activities of daily living, IDDD, Interview to determine deterioration in daily functioning in dementia, MMSE, Mini-mental state examination, NPI, Neuropsychiatric inventory, PGDRS-P, O, B, Psychogeriatric dependency rating scale-physical, orientation, behavior, RAID, Rating of anxiety in dementia, SIRS, Severe impairment rating scale
- DOI : 10.1684/pnv.2012.0375
- Page(s) : 365-72
- Published in: 2012
Background: Dementia is a chronic and evolutive disease, for which no curative treatment exists. Evaluating the quality of life of patients suffering from dementia is therefore an important component of management.
Aims: To summarise existing literature regarding quality of life instruments specific to dementia, and to identify factors associated with quality of life.
Methods: We analysed studies published between November 1996 and December 2010 and referenced in PubMed, and focusing on the development and/or validation of quality of life instruments specific to dementia, or studies having used any such instrument to evaluate a therapeutic intervention.
Results: Nine quality of life instruments were identified. Place of residence and level of education do not appear to play any significant role. Results were conflicting for age and sex. There appears to be a relation, albeit a weak one, with cognitive function. The factors most frequently associated with lower quality of life were behavioural disorders, dependence, and caregiver burden. Quality of life of patients under pharmacological treatment is poorly documented, while occupational therapy and cognitive stimulation appear to have moderate positive effects.