This news is based on the following article: Calderón-Garcidueñas L, Torres-Jardón R, Kulesza RJ, et al. Alzheimer disease starts in childhood in polluted Metropolitan Mexico City. A major health crisis in progress. Environmental Research 2020 ; 183 : 109137. Doi : 10.1016/j.envres.2020.109137
This article reviews and analyzes the results of various studies on the development and progression of Alzheimer disease indicators among different groups of residents in the metropolitan Mexico City area. It focuses on early identification of people at risk of developing Alzheimer disease in so polluted an environment and on understanding the mechanisms involved. The authors provide a wide range of arguments and evidence showing the importance of defining the interactions among environmental, nutritional, metabolic, and genetic risk factors in children to prevent Alzheimer disease for current and future generations.