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Invariant Valpha14 NKT lymphocytes: a double-edged immuno-regulatory T cell population Volume 14, issue 1, March 2003

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CNRS FRE 2444, Paris V, Hôpital Necker, 161 rue de Sèvres, 75743 Paris Cedex 15, France.
  • Page(s) : 4-14
  • Published in: 2003

Introduction The term “natural killer T (NKT)” cells has initially been coined to designate T lymphocytes expressing NK markers, such as NK1.1 (NKR-P1A or CD161). Later on, this population turned out to be quite heterogeneous and it is now well established that it comprises several subsets with distinct functional capacities. The first evidence for NKT cells came from the work of Fowlkes et al. and Budd et al. [1, [...]