John Libbey Eurotext

Bulletin du Cancer


What is new about sentinel lymph node biopsy in breast cancer? Volume 91, issue 4, Avril 2004

Département de chirurgie,, Département de médecine nucléaire,, Département de radiothérapie,, Département d’anatomopathologie,, Département d’oncologie médicale, Institut Paoli-Calmettes, 232 bd Sainte-Marguerite, 13006 Marseille cedex 9

Sentinel lymph node biopsy concept was described in several reports since 1994. Technical and identification procedure, false negative risk, learning curve criteria and benefits concerning cancer stadification and postoperative morbidity were assessed. Peroperative and postoperative pathologic examination procedures are improving progressively but remains still under debate. Classification for micro-metastasis, isolated cells and macro-metastasis in sentinel lymph node was suggested but their immunohistochimic detection and pronostic impact are unclear. These parts are discussed in this article.