Annales de Biologie Clinique


An alarming health check-up: what a bloody plasma! Volume 81, issue 6, November-December 2023


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Biochimie, Centre Hospitalier Régional et Universitaire de Lille, Rue du prof Leclercq 59037 Lille, France
* Correspondance : P. Maboudou

A 35-year-old patient with a metabolic pathology was hospitalized for programmed fibroscopy under general anesthesia for investigation and management of portal hypertension. Following the operation, he showed signs of sepsis and was transferred to intensive care unit. Biological analyzes carried out and generated automaton alarms for certain parameters. A visual check of the appearance of the sample revealed an unusual color of plasma. Additional informations obtained from the clinical department did not provide any explanation for this coloration. Additional assays confirmed an overdose of vitamin B12 related to the treatment of his pathology and which is responsible for the interference observed. Hence the interest of checking the reaction curves in the event of suspected interference and, if necessary, of making dilutions in order to reduce the effects on the biological assays.