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Paraneoplastic sclerodermiform syndrome Volume 30, issue 1, Janvier-Février 2021

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Authors
Service de médecine interne, centre hospitalier de la Polynésie française, Pirae, Tahiti, Polynésie française
* Tirés à part

Systemic scleroderma is a connective tissue disease associated with an increased risk of cancer compared to the general population. A simultaneous occurrence of cancer and systemic scleroderma (or sclerodermo-like syndrome) may also suggest the diagnosis of paraneoplastic sclerodermiform syndrome. Observation: we report a 51 year old woman who was presented with ovarian neoplasia in whom a scleroderma-like syndrome was diagnosed at the occasion of a marked aggravation of her cancer and evoke the diagnosis of paraneoplastic sclerodermiform syndrome. Conclusion: the prevalence of cancers during systemic scleroderma or scleroderma-like syndrome is important and it is also possible that, as in dermatomyositis, we can observe paraneoplastic sclerodermiform syndromes. In addition, it seems important to track cancer in cases of late onset sclerodermiform syndrome, significant general signs, failure response to treatment or positivity of anti-RNA polymerase III antibodies.