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Cahiers d'études et de recherches francophones / Santé

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Long-standing diabetes in Africa and recent ideas about advanced glycation end products: 39 patients in Dakar Volume 17, issue 1, Janvier-Février-Mars 2007

Author
Centre médical Marc Sankalé, BP 5062, Fann Dakar, Sénégal

This study included 39 patients with diabetes followed for a mean period of 27.3 ± 3.9 years. Their mean age was 72.5 ± 10 years and differed significantly between the 7 men (mean age 48.4 ± 7.1 years) and 32 women (mean age 43.4 ± 9.8 years). They resided mainly in urban and suburban areas. Mean body mass index was 29.1 ± 2.9 kg/m 2 in the 87.5% of the patients who were overweight but not obese. Glycemic control differed by sex: for good glycemic control (less than 2 g/L) the sex ratio was 3 women for every 2 men but it was 29 women for 5 men for poor glycemic control (more than 2 g/L). Diastolic blood pressure was normal for 78.9 % of patients. Mean blood cholesterol during the follow-up period ranged between 1.4 ± 0.12 g/L and 2.40 ± 0.1 g/L in 75 % of cases. Only 3 of 39 patients were insulin-dependent. Patients with long-standing diabetes tended to be women and had substantially fewer risk factors than patients with newer diabetes. Moderate chronic complications were nonetheless present: 9 retinopathies; 20 cataracts; 13 with lower-limb peripheral arterial occlusion and 29 cardiac complications.