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Néphrologie & Thérapeutique

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Interest of therapeutic drug monitoring of aminoglycosides administered by a monodose regimen Volume 15, issue 2, Avril 2019

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  • Table 1

  • Table 2

  • Table 3
Authors

1 IntroductionAminoglycosides (AG) have been widely used in clinical practice since 1940s [1]. They are characterized by broad-spectrum antimicrobials that make them effective in the treatment of serious infections caused by Gram-negative bacteria such as Pseudomonas aeruginosa [2].These antibiotics are characterized by a narrow therapeutic index and a large within and between variability in pharmacokinetics. This variability among individuals has been attributed to several factors, such as variation [...]