Médecine et chirurgie du pied


Squamous Cell Carcinoma of the Foot: Epidemiological, Clinical, and Evolutionary Profile about 20 Cases Volume 38, issue 3, Septembre 2022



Cutaneous squamous cell carcinoma (SCC) is a common cancer resulting from the malign proliferation of epidermal keratinocytes. It is the second most common type of skin cancer with the potential for metastasis and recurrence. The most common locations of SCC are the face and the trunk, while foot location is rare. The aim of this study is to describe and analyze the epidemiological, clinical, therapeutically, and evolutionary aspects of patients followed for SCC of the foot.

Materials and methods

A retrospective multicentric study was conducted from January 2000 to December 2020 at the Dermatology Department of the UHC Ibn-Rochd of Casablanca and the National Centre of Leprology of Casablanca.


In total, 20 patients were included in this study, 13 men and 7 women with an average age of 58.74 years. Perforating plantar ulcer (PPU) was found in all ten patients followed for leprosy. The average time of evolution before diagnosis was 18 years. The clinical appearance at diagnosis was dominated by an ulcerating lesion. Amputation was the main treatment in our patients. The evolution was marked by the occurrence of metastases in nine patients. Death occurred for two patients.


The originality of this series lies in the unusual location of SCC in the foot, since the main risk factor is the total dose of ultraviolet (UV) radiation received during lifetime. SCC may arise anew or more often mark the evolution of lesions considered to be noninvasive precursors, such as the malignant transformation of plantar ulcers in leprosy.