John Libbey Eurotext

Hépato-Gastro & Oncologie Digestive


Pharmacological measurements of anti-TNF in IBD: When to do? How to analyze the results? Volume 22, issue 4, Avril 2015


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CHU de Saint-Étienne, service de Gastroentérologie, 42055 Saint-Étienne, cedex 2, France
* Tirés à part

New algorithms based on trough levels of anti-TNF and their antibodies are suggested in patients with inflammatory bowel diseases presenting loss of response under treatment. Conversely, monitoring of trough levels and optimization of treatment without clinical relapse have not proved its usefulness in clinical practice. In case of de-escalation, trough levels could be interesting before to switch to new treatment. The cost-efficacy analysis of trough levels measurements has been reported interesting.