John Libbey Eurotext

Epileptic Disorders

The Educational Journal of the

Use of simultaneous depth and MEG recording may provide complementary information regarding the epileptogenic region Volume 14, issue 3, September 2012

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Authors
Department of Neurology, The Cleveland Clinic, Cleveland, OH, USA, Department of Pediatrics, Tohoku University School of Medicine, Sendai, Japan, Department of Neurosurgery, The Cleveland Clinic, Cleveland, OH, USA, Department of Epileptology, Tohoku University School of Medicine, Sendai, Japan
  • Key words: stereotactic electroencephalography, magnetoencephalography, simultaneous recording, volume conduction, quadratic fall-off
  • DOI : 10.1684/epd.2012.0517
  • Page(s) : 298-303
  • Published in: 2012

Simultaneous SEEG-MEG recording has the potential to define the epileptic spike source accurately. We present a case of a 55-year-old female with intractable left temporal lobe epilepsy in whom we evaluated the relationship between the amplitude recorded from SEEG electrodes, inserted in the lateral temporal region, and their distance from the MEG-modelled spike. We found a quadratic fall-off relationship between the amplitude and distance. This result supports the concept that the MEG dipoles reflect the “centre” of spike locations and may provide comprehensive information for SEEG which records spike activities directly but is inherently limited in spatial sampling.