John Libbey Eurotext

Epileptic Disorders

The Educational Journal of the

Towards a definition of the “practical” epileptogenic zone: a case of epilepsy with dual pathology Volume 8, supplement 2, Supplement 2, September 2006

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Authors
Departments of Neurology and of Neurosurgery, Hôpitaux Universitaires de Strasbourg, University Hospital Robert-Debré, AP-HP, Paris, Department of Functional Neurology and Epileptology, Neurological University Hospital, Hospices Civils de Lyon, Epilepsy Unit, Neurology Dept. Grenoble University Hospital, Grenoble, CTRS-IDEE, Hospices Civils de Lyon, France
  • Key words: epileptogenic zone, epilepsy-surgery, stereo-electroencephalography, depth recordings, dual pathology
  • Page(s) : 67-76
  • Published in: 2006

Presurgical evaluation for patients with drug-resistant epilepsy requires the definition of various zones that have a variable spatial relationship with the epileptogenic zone. All the available mehods to directly measure the actual seizure-onset zone and to define “the minimum amount of cortical tissue that must be resected to produce seizure-freedom” have significant limitations.We report on the case of a patient with dual pathology (hippocampal sclerosis and a post-traumatic scar) and discuss the contribution of the various presurgical investigations that led to surgery and seizure-freedom.