John Libbey Eurotext

Perampanel is effective against Lance-Adams syndrome Volume 23, issue 5, October 2021


Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee, USA
* Correspondence: Kassandra Stubblefield 1161 21st Ave South, A-0118 MCN, Nashville, TN 37232, USA

The development of persistent intention or action myoclonus as a sequela of hypoxic injury was described in detail by Lance and Adams in 1963 [1]. Lance-Adams syndrome (LAS) is a rare chronic post-hypoxic condition characterized by action myoclonus within days to weeks after resuscitation and persists in patients who have recovered consciousness [2-4]. There are no large controlled trials available for guiding treatment for LAS. Among anti-seizure medications, treatment response has been reported [...]