John Libbey Eurotext

Epileptic Disorders

The Educational Journal of the

Involuntary movements after correction of vitamin B12 deficiency: a video-case report Volume 14, issue 2, June 2012

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  • Involuntary movements after correction of vitamin B12 deficiency: a video-case report
  • Involuntary movements after correction of vitamin B12 deficiency: a video-case report

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Authors
Institute for Maternal and Child Health, IRCCS “Burlo Garofolo” Trieste, Department of Pediatrics, General Hospital, San Vito al Tagliamento, Pordenone, Radiology, Institute for Maternal and Child Health, IRCCS “Burlo Garofolo” Trieste, Italy
  • Key words: vitamin B12 deficiency (vB12 deficiency), encephalopathy, involuntary movements, video-EEG
  • DOI : 10.1684/epd.2012.0507
  • Page(s) : 174-80
  • Published in: 2012

Involuntary movements can appear before and after initiation of vitamin B12 treatment. The pathogenesis of involuntary movements in vitamin B12 deficiency and their relationship with cobalamin injection remain unclear due to a lack of video-EEG documentation making the electroclinical correlation difficult to ascertain. Here, we report video-EEG and neuroimaging findings of an 11-month-old girl with vitamin B12 deficiency, who acutely developed involuntary movements a few days after initiation of vitamin B12 treatment with normal vitamin plasmatic levels. Abnormal movements were a combination of tremor and myoclonus involving the face, mouth, and left arm, which disappeared after discontinuation of therapy. [ Published with video sequences]