John Libbey Eurotext

Influence of EEG abnormality localisations on cognitive functions in childhood epilepsies Volume 3, special issue 3, Numéro spécial 2, December 2001

Service de Neuropédiatrie, Hôpital Saint-Vincent-de-Paul, 82, av. Denfert-Rochereau, 75674 Paris Cedex 14, France.

Learning and behavioral disorders are often observed in epileptic children. Nevertheless, most of them have subnormal or normal IQ but exhibit more specific cognitive deficits than mental retardation. Neuropsychological evaluation may provide useful information on the nature and severity of these deficits which interfere with school achievement. Advances in medical knowledge have shown that childhood epilepsy should not be considered as a single disorder but encompasses a whole range of different conditions that exhibit specific clinical, EEG and outcome characteristics. It is known becoming apparent that these various clinical entities have different cognitive expressions that yet need to be specified according to the age of onset and the location of seizure focus. A few neuropsychological studies have demonstrated that both ictal and interictal EEG epileptiform discharges can lead to cognitive deterioration. There is now evidence that the topographic impact of epilepsy needs to be considered in epileptic children to optimize their cognitive evaluation and guide their neuropsychological rehabilitation.