Department of Child Neurology, Brain Center, University medical Center Utrecht, Member of the European Reference Network EpiCARE, The Netherlands
Children's Department, Danish Epilepsy Centre, Dianalund, Denmark
HUS Medical Imaging Center, Clinical Neurophysiology, University of Helsinki, Helsinki University Hospital and University of Helsinki, Finland
Correspondence: FE. Jansen
Department of Child Neurology, Brain Center Rudolf Magnus,
University Medical Center,
Heidelberglaan 100, 3584 CX Utrecht, Holland
The major goal of therapy in patients with Encephalopathy related to Status Epilepticus during slow Sleep (ESES) is to prevent or reduce associated cognitive deficits. Whether or not the EEG pattern of ESES should be completely suppressed to improve cognition is unknown. In clinical practice, there are two major challenges: to establish the optimal treatment strategy in patients with ESES, and to identify the patients who will benefit most from therapy, including atypical cases. Here, we provide a comprehensive overview of the current literature on treatment efficacy in patients with ESES.