John Libbey Eurotext

Epileptic Disorders

The Educational Journal of the

A case of levetiracetam-induced thrombocytopenia Volume 12, issue 4, December 2010


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Department of Neurology, University Hospitals Case Medical Center, University Hospitals Case Medical Center, Division of Hematology/Oncology and Department of Neurology, Cleveland, Ohio, USA
  • Key words: glioblastoma multiforme, seizures, levetiracetam, thrombocytopenia
  • DOI : 10.1684/epd.2010.0343
  • Page(s) : 335-7
  • Published in: 2010

Rare cases of levetiracetam-induced thrombocytopenia have been reported in the literature. We report a case of glioblastoma multiforme and partial epilepsy treated with levetiracetam with subsequent development of thrombocytopenia. After ruling out all other possible causes of a decreased platelet count, we conclude that levetiracetam was the cause of this adverse event.