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European Journal of Dermatology

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Autoimmune bullous dermatoses: should we treat the patient or the antibodies? A preliminary study Volume 32, issue 2, March-April 2022

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Authors
1 Section of Dermatology, Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy
2 Department of Experimental Medicine (DIMES), University of Genoa, Genoa, Italy
3 Section of Statistics, Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy

  Serological detection of autoantibodies via indirect immunofluorescence (IIF) and enzyme-linked immunosorbent assays (ELISA) is usually helpful in the diagnostic process of autoimmune bullous dermatoses (AIBDs) [1]. ELISA provides objective and quantitative results, which may better reflect disease activity than those of IIF [1]. In fact, the titre of antibodies is reported to correlate with disease activity over time, especially anti-desmoglein (anti-Dsg) -1 and -3 in patients with pemphigus [...]