John Libbey Eurotext

Bulletin du Cancer


Breast carcinoma and genomic technology: contribution of DNA microarrays Volume 91, issue 4, Avril 2004


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Plateforme de génomique, Service de biochimie et biologie moléculaire, Hôpital Lariboisière (AP-HP), 2, rue Ambroise Paré, 75010 Paris, Service d’oncologie médicale, Groupe hospitalier Diaconesses-Croix Saint-Simon, 18 rue du Sergent Bauchat, 75571 Paris Cedex 12

Genome wide expression analyses techniques are now applied to breast carcinoma. Several results have been achieved : molecular clustering of breast carcinomas, implementation of powerful prognostic classifications, and in some way predictive classification. Unfortunately, translation to bedside remains limited due to standardization difficulties.