John Libbey Eurotext

Médecine thérapeutique / Pédiatrie


Henoch-Schönlein purpura Volume 14, issue 5-6, Septembre-Décembre 2011


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Hôpital Necker, rhumatologie pédiatrique, 149, rue de Sèvres, 75015 Paris, France
  • Key words: leucocytoclastic vasculitis, purpura, immunoglobulin A, glomerulonephritis, corticosteroids
  • DOI : 10.1684/mtp.2011.0411
  • Page(s) : 349-54
  • Published in: 2011

Henoch-Schönlein purpura (HSP) is an acute small-vessel leucocytoclastic vasculitis, which is the most common vasculitis in children. In most cases, HSP is a self-limited condition, which resolves spontaneously. Nephritis is the one feature of HSP that may have chronic consequences, and the long-term prognosis heavily depends on the severity of nephritis. Renal biopsy has to be promptly discussed in children who present with proteinuria greater than 0,5 g/L, renal insufficiency and/or nephrotic syndrome.