- Auteur(s) : Brigitte Bader-Meunier
, Hôpital Necker,
149, rue de Sèvres,
- Mots-clés : leucocytoclastic vasculitis, purpura, immunoglobulin A, glomerulonephritis, corticosteroids
- Page(s) : 349-54
- DOI : 10.1684/mtp.2011.0411
- Année de parution : 2011
Henoch-Schönlein purpura (HSP) is an acute small-vessel leucocytoclastic vasculitis, which is the most common vasculitis in children. In most cases, HSP is a self-limited condition, which resolves spontaneously. Nephritis is the one feature of HSP that may have chronic consequences, and the long-term prognosis heavily depends on the severity of nephritis. Renal biopsy has to be promptly discussed in children who present with proteinuria greater than 0,5 g/L, renal insufficiency and/or nephrotic syndrome.