John Libbey Eurotext

Journal de Pharmacie Clinique


Menstrual toxic shock syndrome: a case report Volume 36, issue 1, Mars 2017


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1 Service de pharmacie, Hôpital Antoine Béclère, Clamart, France
2 Service de bactériologie, Hôpital Antoine Béclère, Clamart, France
* Tirés à part
  • Key words: toxic shock syndrome, Staphylococcus aureus, TSST-1, periodic tampon, prevention
  • DOI : 10.1684/jpc.2017.0350
  • Page(s) : 43-8
  • Published in: 2017

Menstrual toxic shock syndrome (mTSS) is a rare but serious disease with multiorgan failure. It occurs mainly in young women using super-absorbent tampon material. The present article documents the case of a young 19-year-old woman, with no history, having developed a mTSS after tampon use. Laboratory investigations revealed a toxigenic strain of Staphylococcus aureus producing toxic shock syndrome toxin (TSST-1). Resuscitative mesures and appropriate antibiotic therapy led to favorable outcome despite cardiac complications after administration of vasopressors. Nowadays, the patient's recovery is complete. Providing the good use of gynecology medical devices, especially in high-risk patients participate in disease prevention to limit the development of mTSS associated with complications and death. These widely used manufacturing products are not without risk. Among healthcare professionals involved in these patients’ management, pharmacists could have a major place in the counseling about menstrual material, absorbency rating and risk connected with an extended wear and as well as referring patients for urgent management in case of suspicion of mTSS.