CHP Rennes Saint Grégoire, 6 boulevard de la Boutière, 35760 Saint Grégoire, France
Anoperineal lesions are common in patients with Crohn's disease, with 43% cumulative probability to occur after 20 years, 26% for suppurations. They significatively impact quality of life of patients and are associated with fecal incontinence. Treatment of fistula is a medicosurgical challenge, with disppointing results. Anti-TNF agents are the best evaluated treatments, they are used in first intention, most often after seton drainage.
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