UMR 1086 INSERM “Anticipe” Centre François Baclesse 14000 Caen
Service de chirurgie hépatobiliaire et pancréatique, centre hospitalier et universitaire de Caen, avenue de la côte de Nacre, 14032 Caen
Faculté de médecine de Caen, 2 avenue des Rochambelles, 14033 Caen cedex
The cholangiocarcinoma account for less than 3% of digestive neoplasms. This tumor is subdivided in two categories, extrahepatic and intrahepatic cholangiocarcinoma, which is divided into peri-hilar cholangiocarcinoma and low bile duct cholangiocarcinoma. The lack of a specific topographic code for peri-hilar cholangiocarcinoma makes clinical research difficult and calls into question the reliability of historical studies. The risk factors associated with this type of cancer are geographically variable, which consequently explains the different incidence rates estimated worldwide. Hepatic steatosis and obesity are increasing in Western countries that reflect the increased incidence rates of cholangiocarcinoma in these countries. In France, the incidence of cholangiocarcinoma is increasing in both sex except for extrahepatic cholangiocarcinoma that is decreasing in women. Assigning a specific topographic code to perihilar cholangiocarcinoma seems crucial in order to have reliable studies.