John Libbey Eurotext

Hématologie

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Anemia in the elderly: study of links with geriatric criteria Volume 23, issue 6, Novembre-Décembre 2017

Authors
1 Département de médecine interne-gériatrie-thérapeutique, CHU Rouen, 76000 Rouen, France
2 Interne de santé publique, département de pharmacovigilance-santé publique, CHU Rouen, 76000 Rouen, France
3 Département de médecine interne, CHRU Strasbourg, 67000 Strasbourg, France
* Tirés à part

Introduction: The aim is to study the links between anemia and geriatric criteria. Patients and methods: Prospective study carried out in an acute geriatric unit, at CHU Rouen, from May 1st 2016 to July 31st 2016 inclusive. The anemia defined by Hb <12 g/dL whatever the sex. Two analyzes were systematically performed: a bivariate analysis of the average (mean FRIED) of the anemic subjects to the mean of the non-anemic subjects; A multivariate analysis of outcomes FRIED SEGA ADL and IADL adjusted to anemia, age, sex, albuminemia and a history of heart failure. Results: 141 patients included, of whom 67 were anemic (57.5 %) and 74 were non-anemic (42.5 %). 89 Women (63.1 %). The average age of 86.7 years.7 deaths are recorded in the department. In bivariate analysis, anemic patients are more fragile, as evidenced by the Fried score (3.88 IC95 [3.64; 4.12] versus non-anemic subjects: 2.01 IC95 [1.73; 2.30], p <0.0001) SEGA (18.04 IC95 [17.22; 18.87] versus non-anemic subjects: 12.01 IC95 [10.90; 13.12], p <0.0001). In multivariate analysis, the FRIED score was increased by 1.89 (1.52; 2.27) in anemic patients compared to non-anemic patients. Adjusted to albuminemia, age, sex and heart failure, the result is virtually unchanged 1.84 (1.47; 2.21) and remains significant (p <0.0001). Regarding SEGA, IADL and ADL, the results are significant and independent to albuminemia, age, sex and heart failure. Conclusion: The link between frailty and anemia seems strong. The meaning of this association remains to be determined.