John Libbey Eurotext

Environnement, Risques & Santé


Exposome et AOP : deux concepts à conjuguer pour mieux comprendre les effets de l’environnement chimique Volume 17, issue 1, January-February 2018


This news is based on the following article: Escher BI, Hackermüller J, Polte T, et al. From the exposome to mechanistic understanding of chemical-induced adverse effects. Environ Int 2017; 99: 97-106. doi: 10.1016/j.envint.2016.11.029


Integrating the concept of adverse outcome pathways(AOP) to that of the exposome can further our understanding of the mechanistic links between chemical exposure and disease, according to these authors, who discuss the opportunities and difficulties of this integration.