John Libbey Eurotext

Epileptic Disorders

The Educational Journal of the

Transcranial direct current stimulation improves seizure control in patients with Rasmussen encephalitis Volume 18, issue 1, March 2016


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1 Department of Neurology, Istanbul Faculty of Medicine, Istanbul University
2 Department of Physiology, Istanbul Bilim University
3 Department of Physiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul
4 Department of Psychology, Centre for Speech, Language and the Brain, University of Cambridge, Cambridge, UK
5 Department of Neurology, Okmeydani Education and Research Hospital, Istanbul, Turkey
* Correspondence: Pinar Tekturk Department of Neurology, Division of Clinical Neurophysiology, Istanbul Faculty of Medicine, Istanbul University, Millet street, Capa, Fatih, Istanbul 34093, Turkey
  • Key words: direct current stimulation, Rasmussen encephalitis, epilepsy
  • DOI : 10.1684/epd.2016.0796
  • Page(s) : 58-66
  • Published in: 2016


Rasmussen encephalitis is associated with severe seizures that are unresponsive to antiepileptic drugs, as well as immunosuppressants. Transcranial direct current stimulation (t-DCS) is a non-invasive and safe method tried mostly for focal epilepsies with different aetiologies. To date, there is only one published study with two case reports describing the effect of t-DCS in Rasmussen encephalitis. Our aim was to investigate the effect of t-DCS on seizures in Rasmussen encephalitis and to clarify its safety.