John Libbey Eurotext

Transcranial direct current stimulation improves seizure control in patients with Rasmussen encephalitis Volume 18, issue 1, March 2016


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1 Department of Neurology, Istanbul Faculty of Medicine, Istanbul University
2 Department of Physiology, Istanbul Bilim University
3 Department of Physiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul
4 Department of Psychology, Centre for Speech, Language and the Brain, University of Cambridge, Cambridge, UK
5 Department of Neurology, Okmeydani Education and Research Hospital, Istanbul, Turkey
* Correspondence: Pinar Tekturk Department of Neurology, Division of Clinical Neurophysiology, Istanbul Faculty of Medicine, Istanbul University, Millet street, Capa, Fatih, Istanbul 34093, Turkey


Rasmussen encephalitis is associated with severe seizures that are unresponsive to antiepileptic drugs, as well as immunosuppressants. Transcranial direct current stimulation (t-DCS) is a non-invasive and safe method tried mostly for focal epilepsies with different aetiologies. To date, there is only one published study with two case reports describing the effect of t-DCS in Rasmussen encephalitis. Our aim was to investigate the effect of t-DCS on seizures in Rasmussen encephalitis and to clarify its safety.