John Libbey Eurotext

Epileptic Disorders

The Educational Journal of the

Multifocal dysembryoplastic neuroepithelial tumours associated with refractory epilepsy Volume 16, issue 3, September 2014

Figures

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Authors
1 Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda
  • Key words: multi-focal tumor, tumor-associated epilepsy, Chiari malformation
  • DOI : 10.1684/epd.2014.0680
  • Page(s) : 328-32
  • Published in: 2014

Dysembryoplastic neuroepithelial tumours (DNET) are a common cause of tumour-associated epilepsy, and are usually located in the temporal lobes. We present a case of multifocal DNETs in both infra- and supra-tentorial locations, in a 23-year-old man with a coincident Type I Chiari malformation, presenting with medically refractory focal seizures. The extensive anatomical distribution of the lesions suggests a genetic component in their tumourigenesis.