Epileptic Disorders
MENUMultifocal dysembryoplastic neuroepithelial tumours associated with refractory epilepsy Volume 16, numéro 3, September 2014
Auteurs
1 Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda
- Mots-clés : multi-focal tumor, tumor-associated epilepsy, Chiari malformation
- DOI : 10.1684/epd.2014.0680
- Page(s) : 328-32
- Année de parution : 2014
Dysembryoplastic neuroepithelial tumours (DNET) are a common cause of tumour-associated epilepsy, and are usually located in the temporal lobes. We present a case of multifocal DNETs in both infra- and supra-tentorial locations, in a 23-year-old man with a coincident Type I Chiari malformation, presenting with medically refractory focal seizures. The extensive anatomical distribution of the lesions suggests a genetic component in their tumourigenesis.