John Libbey Eurotext

Epileptic Disorders

The Educational Journal of the International League Against Epilepsy

Gelastic seizures: not always hypothalamic hamartoma Volume 9, issue 4, December 2007


  • Gelastic seizures: not always hypothalamic harmatoma


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Epilepsy Programme, Department of Clinical Neurological Sciences, University of Western Ontario, London, Canada
  • Key words: gelastic seizures, cortical dysplasia, hypothalamic hamartoma frontal lobe seizures
  • DOI : 10.1684/epd.2007.0139
  • Page(s) : 453-8
  • Published in: 2007

Gelastic seizures are often associated with hypothalamic hamartomas. However, focal cortical dysplasias can also cause “laughing seizures”, and such cases can be difficult to localize with EEG. This case report presents a 29-year-old woman who was successfully rendered free of gelastic seizures after resection of a frontal cortical dysplasia, localized through MRI and SPECT imaging.[Published with video sequences]