Service de Dermatologie, Hôpital Fournier, 36, quai de la Bataille, F-54000 Nancy, France.
- Key words: aphthous stomatitis, nicorandil.
- Page(s) : 132-3
- Published in: 2000
Aphthous stomatitis may be drug-induced. Here we report the first two cases of major aphthous stomatitis induced by nicorandil, a new potassium-channel activator. A dosage increase, a high-dose treatment or a history of minor aphthous stomatitis may be considered as important cofactors.