John Libbey Eurotext

European Journal of Dermatology


Major aphthous stomatitis induced by nicorandil Volume 7, issue 2, March 1997


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Service de Dermatologie, Hôpital Fournier, 36, quai de la Bataille, F-54000 Nancy, France.
  • Key words: aphthous stomatitis, nicorandil.
  • Page(s) : 132-3
  • Published in: 2000

Aphthous stomatitis may be drug-induced. Here we report the first two cases of major aphthous stomatitis induced by nicorandil, a new potassium-channel activator. A dosage increase, a high-dose treatment or a history of minor aphthous stomatitis may be considered as important cofactors.