John Libbey Eurotext

European Journal of Dermatology

Cutaneous Rosai-Dorfman disease associated with uveitis Volume 27, issue 1, January-February 2017

Figures

  • Figure 1
Authors
1 Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017,
2 Department of Infection and Host Defense, Graduate School of Medicine, Chiba University, 1-8-1 Inohara, Chuo-ku, Chiba 260-8670,
3 Department of Dermatology, Kobe Accident Hospital, 4-1-23 Kagoike-dori, Chuo-ku, Kobe 651-0053,
4 Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan

Rosai-Dorfman disease (RDD) was originally described as a rare pseudolymphomatous disorder, characterised by persistent massive lymphadenopathy and caused by increased numbers of macrophages within lymph node sinuses [1, 2]. These macrophages are often large and exhibit abnormal behaviour, taking intact cells, such as lymphocytes, erythrocytes, and plasma cells, into the cytoplasm, as a phenomenon known as emperipolesis. Population sites of these abnormal macrophages are not confined to lymph node [...]