John Libbey Eurotext

Annales de Biologie Clinique


Optimization of pre-analytical conditions for measurement of biomarkers in seminal plasma: application to adipokines Volume 75, issue 6, Novembre-Décembre 2017


1 Service de biologie de la reproduction, Hôpital Tenon, AP-HP, Université Pierre et Marie Curie Paris 6, Paris, France
2 Sorbonne universités, UPMC Université Paris 06, Inserm UMRS_938, Centre de Recherche Saint-Antoine, IHU ICAN, Paris, France
3 UF biomarqueurs inflammatoires et métaboliques, Service de biochimie et hormonologie, Hôpital Tenon, AP-HP, Paris, France
4 INRA, UMR85, Physiologie de la reproduction et des comportements, Nouzilly, France
5 Service d’endocrinologie, Hôpital Saint-Antoine, AP-HP, Paris, France

A link between obesity and male infertility, concerning particularly semen quality, has been reported [1-3]. Indeed, circulating levels of adipokines, bioactive peptides secreted by adipose tissue [4], are correlated with sperm quality in both animals and humans [1, 2]. In this context, levels of adipokines in seminal plasma could influence sperm function and represent useful biomarkers to evaluate fertility-related physiological and pathophysiological conditions and to further appreciate their [...]