Laboratoire de virologie moléculaire et immunologie, UR086 INRA Bio-agresseurs, Santé et Environnement, Centre INRA de Tours, 37380 Nouzilly, Laboratoire virologie et barrière d’espèces, UR086 INRA Bio-agresseurs, Santé et Environnement, Centre INRA de Tours, 37380 Nouzilly
In the late 1980’s, a new retroviral pathology called myelocytomatosis emerged in some chicken flocks in the United Kingdom and rapidly spread worldwide, including France. The virus responsible for this disease was classified into a new subgroup of retroviruses, the avian leukosis virus subgroup J (ALV-J). We are reporting herein the unique genomic and biological characteristics of ALV-J, including novel retroviral endogenous sequences. Even though the ALV-J outbreak was rapidly controlled, it shows that there is a high risk of appearance of new pathogenic avian retroviruses.