Médecine et chirurgie du pied


Intraarticular injection of adalimumab in localized psoriatic arthritis Volume 25, issue 4, Décembre 2009


A 67-year-old man with tarsitis and psoriatic arthritis of the right ankle, not controlled by standard treatment (anti-inflammatories, methotrexate 20 mg weekly, and totally ineffective corticoid injection of the ankle), was given an intraarticular injection of adalimumab after a period of careful supervision. The improvement of blood results and magnetic resonance imaging (MRI) changes after injection (MRI before injection, then 10 months and 24 months later) were clear. The occurrence of algodystrophy around the right ankle 6 months after the injection was followed by improvement over several months. The clinical improvement of this monoarthritis of the right ankle has been maintained during the 4 years since the injection.